Managing big issues on lean evidence: treating obesity hypertension

Managing big issues on lean evidence: treating obesity hypertension.

Obesity, defined as a body mass index (BMI) greater than 30 kgum, is an important risk factor for hypertension, and excess adiposity is believed to account for 70% of hypertension in men and 60% in women w1,2x. There is now accumulating evidence that adipose tissue may itself be involved directly in the pathogenesis of hypertension, not only by contributing to an increase in sympathetic activit...

Managing weighty issues on lean evidence: the challenges of bariatric medicine.

Drug Mechanisms to Help in Managing Resistant Hypertension in Obesity

Obesity is a major risk factor for the development of hypertension. Because the prevalence of obesity is increasing worldwide, the prevalence of obesity hypertension is also increasing. Importantly, hypertension in obesity is commonly complicated by dyslipidemia and type 2 diabetes mellitus and hence imposes a high cardiovascular disease risk. Furthermore, obesity is strongly associated with re...

Obesity-related hypertension?: weighing the evidence.

Overweight and obesity are established risk factors for hypertension, and hypertension is approximately twice as prevalent in the obese than in the nonobese. The prevalence of overweight and obesity has been increasing in the United States for at least the past 2 decades. These increases have occurred in children, adolescents, and adults, as well as in both genders and in all racial/ethic group...

Public health issues and intervention programs in hypertension. Some public policy concerns in managing hypertension.

In analyzing policy concerns related to hypertension management, recommendations must be based on sound science. Where uncertainties remain about the causes and management of hypertension, decisions and recommendations should be appropriate to the known science and foster resolution of uncertainty. Obesity control and sodium restriction can be useful in the management of hypertension but may re...